Key Findings

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. Each key finding is below the article title, with a link to the abstract. 


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Current List - August 2020

Acceptability and efficacy of naltrexone for criminal justice‐involved individuals with opioid use disorder: a systematic review and meta‐analysis

Naltrexone appears to be efficacious and acceptable for the treatment of opioid use disorder among criminal justice‐involved individuals.

Link to Abstract

Association between mortality rates and medication and residential treatment after in‐patient medically managed opioid withdrawal: a cohort analysis

Among people who have undergone medically managed opioid withdrawal, receipt of medications for opioid use disorder, residential treatment, or a combination of the two were associated with substantially reduced mortality compared with no treatment.

Link to Abstract

Cardiovascular and neuropsychiatric safety of smoking cessation pharmacotherapies in non‐depressed adults: a retrospective cohort study

Compared with nicotine replacement therapy, varenicline does not appear to be associated with an increased risk of cardiovascular or neuropsychiatric hospitalizations.

Link to Abstract

Cost‐effectiveness of the HepCATT intervention in specialist drug clinics to improve case‐finding and engagement with HCV treatment for people who inject drugs in England

Increasing hepatitis C virus (HCV) infection case‐finding and treatment referral in drug treatment centres could be a highly cost‐effective strategy for decreasing HCV incidence among people who inject drugs.

Link to Abstract

Counseling alone or in combination with nicotine replacement therapy for treatment of black non‐daily smokers: a randomized trial

Among black non‐daily smokers in the US, adding NRT to counselling did not appear to improve quit success rates.

Link to Abstract

Drinking beyond the binge threshold in a clinical sample of adolescents

Among US adolescents with alcohol‐related problems followed‐up in young adulthood, standard threshold binge drinking (5+ drinks per occasion) was associated with fewer alcohol‐related consequences and problem behaviors than drinking beyond the standard binge threshold.

Link to Abstract

Estimated changes in hospital admissions for alcohol intoxication after partial bans on off‐premises sales of alcoholic beverages in the canton of Vaud, Switzerland: an interrupted time-series analysis

Partial restrictions of off‐premises sales of alcohol in Switzerland (only 2 days per week or only for beer and spirits) appeared to reduce hospital admissions for alcohol intoxication across a wide range of ages.

Link to Abstract

Family structure and alcohol use disorder: a register‐based cohort study among offspring with and without parental alcohol use disorder

The prevalence of non‐intact family structure appears to be higher in offspring of parents with alcohol use disorder (AUD) than among offspring from the general population. Both parental AUD and non‐intact family structure appear to be associated with increased risk of offspring AUD.

Link to Abstract

Impact of Qingdao's smoke‐free legislation on hospitalizations and mortality from acute myocardial infarction and stroke: an interrupted time–series analysis

The 2013 smoke‐free legislation in Qingdao, China was associated with reduction in hospitalization from acute myocardial infarction and stroke among permanent residents aged 35 years or older.

Link to Abstract

Patterns of alcohol consumption in 16 cohorts of Australian young adults aged 15–24 between 2001 and 2016

Recent decreases in adolescent drinking in Australia may be due in part to lower consumption in recent cohorts of younger drinkers.

Link to Abstract

Prospective association of e‐cigarette and cigarette use with alcohol use in two waves of the Population Assessment of Tobacco and Health

In the US between 2013 and 2015, after adjustment for socio‐demographic characteristics, cigarette and e‐cigarette use were associated with alcohol use 1 year later.

Link to Abstract

Reaching out to big losers leads to sustained reductions in gambling over 1 year: a randomized controlled trial of brief motivational contact

Providing high‐expenditure gamblers in Norway with individualized feedback on expenditures was associated with reduced theoretical losses and greater use of responsible gambling tools over a 12‐month period, compared with no contact.

Link to Abstract

Systematic review and meta‐analysis of the moderating effect of rs1799971 in OPRM1, the mu‐opioid receptor gene, on response to naltrexone treatment of alcohol use disorder

From the evidence to date, it remains unclear whether rs1799971, the OPRM1 Asn40Asp single nucleotide polymorphism, predicts naltrexone treatment response in individuals with alcohol use disorder or heavy drinking.

Link to Abstract

The cascade of care for opioid use disorder: a retrospective study in British Columbia, Canada

People with opioid use disorder in British Columbia, Canada receive high levels of out‐patient care prior to diagnosis.

Link to Abstract