Key Findings

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. Each key finding is below the article title, with a link to the abstract. 


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Current List - July 2022

Alcohol consumption in India: a systematic review and modelling study for sub-national estimates of drinking patterns

Alcohol use in India has large regional variations.

Link to Abstract

Alcohol consumption trajectories over the Australian life course

In Australia, average daily alcohol consumption and frequency of consumption peak in middle age.

Link to Abstract

Alcohol demand as a predictor of drinking behavior in the natural environment

Alcohol demand appears to be associated with when and how much people drink.

Link to Abstract

Association of smoking, lung function and COPD in COVID-19 risk: a two-step Mendelian randomization study

There is genetic evidence that smoking likely increases the risk of severe COVID-19.

Link to Abstract

Can PATH Study susceptibility measures predict e-cigarette and cigarette use among American youth 1 year later?

E-cigarette and cigarette susceptibility measures predict product-specific use among youth 1 year later.

Link to Abstract

Clarifying gambling subtypes: the revised pathways model of problem gambling

A revised Pathways Model of problem gambling includes key differences in the relationship between Pathways 2 and 3.

Link to Abstract

Does genetic variation in a bitter taste receptor gene alter early smoking behaviours in adolescents and young adults?

Adolescents who can taste bitter compounds appear to escalate more quickly to monthly smoking and tobacco dependence and have higher nicotine intake

Link to Abstract

Dosing profiles of concurrent opioid and benzodiazepine use associated with overdose risk among US Medicare beneficiaries: group-based multi-trajectory models

Patterns of overdose risk among US Medicare patients are linked to very-high-dose opioid use, high-dose benzodiazepine use, and medium-dose opioid with low-dose benzodiazepine use

Link to Abstract

Duration of use and outcomes among people with opioid use disorder initiating methadone and buprenorphine in Ontario: a population-based propensity-score matched cohort study

Treatment retention and overdose risk are higher among methadone recipients compared with buprenorphine recipients in Ontario, Canada

Link to Abstract

Efficacy of non-invasive brain stimulation interventions in reducing smoking frequency in patients with nicotine dependence: a systematic review and network meta-analysis of randomized controlled trials

Prefrontal noninvasive brain stimulation interventions appear to reduce the number of cigarettes smoked with good acceptability.

Link to Abstract

Evidence on the acute and residual neurocognitive effects of cannabis use in adolescents and adults: a systematic meta-review of meta-analyses

Meta-analytical data show that cannabis intoxication leads to deficits in several cognitive domains that may persist beyond the period of acute intake.

Link to Abstract

Functional connectivity in the central executive network predicts changes in binge drinking behavior during emerging adulthood: an observational prospective study

Functional pathways within the brain's central executive network may contribute to changes in problematic drinking behaviors

Link to Abstract

HIV clinic-based extended-release naltrexone versus treatment as usual for people with HIV and opioid use disorder: a non-blinded, randomized non-inferiority trial

HIV-clinic-based XR-naltrexone may not be inferior to treatment as usual for achieving HIV viral suppression

Link to Abstract

Mortality and negative outcomes of opioid use and opioid use disorder: a 6-year follow-up study

In Iran, opioid use and opioid use disorder are associated with increased mortality.

Link to Abstract

Parental substance use disorder and offspring not in education, employment or training: a national cohort study of young adults in Sweden

In Sweden, exposure to parental SUD before age 17 is associated with increased risk of being not in education, employment or training in early adulthood.

Link to Abstract

Relationship between high-risk alcohol consumption and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroconversion: a prospective sero-epidemiological cohort study among American college students

Among US college students, high-risk drinking may be associated with higher risk for SARS-C0V-2 infection.

Link to Abstract

Risk of self-harm or suicide associated with specific drug use disorders, 2004–2016: a population-based cohort study

In Hong Kong, drug use disorders are associated with increased risk of self-harm or suicide.

Link to Abstract

The association between recreational cannabis legalization, commercialization and cannabis-attributable emergency department visits in Ontario, Canada: an interrupted time–series analysis

In Canada, cannabis attributable emergency department visits decreased following recreational cannabis legalization with strict retail controls.

Link to Abstract

The effects of cannabis and alcohol on driving performance and driver behaviour: a systematic review and meta-analysis

Cannabis combined with alcohol is more detrimental to driving performance than either in isolation.

Link to Abstract

Trajectories of alcohol consumption in relation to all-cause mortality in patients with cardiovascular disease: a 35-year prospective cohort study

There is no evidence that patients who consistently drink ≤14 units/week have a lower mortality risk than long-term abstainers

Link to Abstract

Trajectories of e-cigarette advertising exposure, e-cigarette use and cigarette smoking in a sample of young adults from Hawaii

Increased exposure to e-cigarette advertising appears to be associated with increased e-cigarette use.

Link to Abstract