Comparative clinical effectiveness and safety of tobacco cessation pharmacotherapies and electronic cigarettes: a systematic review and network meta-analysis of randomized controlled trials

Most smoking cessation therapies are more effective than placebo at helping participants achieve sustained abstinence; varenicline is most effective.

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Effect of reductions in opioid prescribing on opioid use disorder and fatal overdose in the United States: a dynamic Markov model

Reduced opioid prescribing in the US appears to have saved about 9,600 lives and may save another 50,000 by 2029.

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Patient characteristics and treatment utilization in fatal stimulant-involved overdoses in the United States Veterans Health Administration

The rate of deaths among US Veterans from stimulant-related overdose was three times higher in 2018 than 2012.

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