Key Findings

This is a quick summary of the main discovery for each research paper we have published, organized issue by issue. Each key finding is below the article title, with a link to the abstract. 


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October 2022

The effectiveness of psychosocial interventions at reducing the frequency of alcohol and drug use in parents: findings of a Cochrane Review and meta-analyses

Integrated psychosocial interventions for parenting and substance use may be better at reducing parental alcohol and drug use

Link to Abstract

Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis

There are too few high-quality trials of pharmacotherapies for alcohol withdrawal to measure their comparative performance.

Link to Abstract

The representation of females in clinical trials for substance use disorder conducted in the United States (2010–19)

In 316 US clinical trials for substance use disorder completed between 2010 and 2019, only 8% reported sex-specific analyses.

Link to Abstract

Assessing the impacts of alcohol outlets on crime as a natural experiment: agglomeration, churning and spatial effects

Bar, pub, and restaurant openings appear to be related to increases in neighborhod crime in Oakland, California.

Link to Abstract

Impact of fentanyl use on initiation and discontinuation of methadone and buprenorphine/naloxone among people with prescription-type opioid use disorder: secondary analysis of a Canadian treatment trial

Buprenorphine/naloxone and methadone may be appropriate treatment options for people with prescription-type OUD regardless of fentanyl exposure

Link to Abstract

Domestication of drinking: a survey study of changes in types of drinking occasions during periods of increasing and decreasing alcohol consumption in the 2000s in Finland

The rise in per-capita drinking in Finland was linked to an increase in lighter drinking occasions at home either alone or with family

Link to Abstract

Effects of e-cigarette use on mental health among youths: quasi-experimental evidence from Canada

Canadian e-cigarette minimum legal age law has reduced risks of mood and anxiety disorders, lowered substance use and improved peer relationships

Link to Abstract

The relationship between smokeless tobacco (snus) and anxiety and depression among adults and elderly people. A comparison to smoking in the Tromsø Study

In Norway, current snus users have a higher socioeconomic status than current smokers and no detectable association with anxiety and depression

Link to Abstract

Characterising the use of varenicline: an analysis of the Australian dispensing claims data

Australians dispensed varenicline appear to be healthier compared with those who are dispensed NRT or bupropion

Link to Abstract

Familial associations in adolescent substance use disorder: a population-based cohort study

A family history of substance use disorder appears to be associated with increased SUD risk in adolescents

Link to Abstract

Towards optimum smoking cessation interventions during pregnancy: a household model to explore cost-effectiveness

A model for estimating cost-effectiveness of smoking interventions for pregnant women found that a hypothetical intensive intervention would be cost-effective

Link to Abstract

Age–period–cohort analysis of trends in tobacco smoking, cannabis use, and their co-use in the Australian population

There has been a consistent decrease in exclusive tobacco smoking across age, period and birth cohorts between 2001-2019 in Australia

Link to Abstract

Recreational cannabis legalization and transitions in cannabis use: findings from a nationally representative longitudinal cohort in the United States

Recreational cannabis legalization in the US may be associated with elevated odds of transition to cannabis use

Link to Abstract

Modeling the cost-effectiveness and impact on fatal overdose and initiation of buprenorphine–naloxone treatment at syringe service programs

Offering buprenorphine treatment within syringe service programs might decrease fatal overdoses, improve treatment engagement, and save money

Link to Abstract

Prenatal smoking, alcohol and caffeine exposure and offspring externalizing disorders: a systematic review and meta-analysis

There is no clear evidence for a causal relationship between maternal prenatal smoking and offspring ADHD.

Link to Abstract